Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442758 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2NPSR1MAPTKMT2AALDH1A1 | |
| SCHEMBL7438489 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTKMT2AADRB2ADRB1 | |
| SCHEMBL4138810 | 0.82 | MAPT (0.37) | SMN1; SMN2MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL5186572 | 0.78 | KMT2A (0.55) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL10724843 | 0.76 | ALOX15 (0.44) | ALOX15NPSR1MAPTKMT2AGAA | |
| SCHEMBL14832746 | 0.75 | CA12 (0.47) | SMN1; SMN2MAPTKMT2AGAAGLA | |
| SCHEMBL1310538 | 0.74 | NPSR1 (0.43) | ALOX15SMN1; SMN2NPSR1MAPTKMT2A | |
| SCHEMBL19511782 | 0.73 | ITGA4 (0.53) | MAPTKMT2AMMP1 | |
| SCHEMBL19511781 | 0.73 | ITGA4 (0.53) | MAPTKMT2AMMP1 | |
| SCHEMBL6768253 | 0.73 | POLB (0.50) | ALOX15SMN1; SMN2MAPTKMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |