Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445535 | 0.87 | ALOX15 (0.42) | SMN1; SMN2KMT2AMAPTADRB2ADRB1 | |
| SCHEMBL7442758 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMAPT | |
| SCHEMBL16244682 | 0.81 | CTSS (0.48) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL5186572 | 0.77 | KMT2A (0.55) | SMN1; SMN2KMT2APTPRCMAPT | |
| SCHEMBL4155668 | 0.73 | MAPT (0.34) | SMN1; SMN2KMT2APTPRCKDM4EMAPT | |
| SCHEMBL5246965 | 0.73 | CTSS (0.48) | SMN1; SMN2KMT2APTPRC | |
| SCHEMBL19511843 | 0.73 | ITGA4 (0.50) | ESR1ESR2KMT2AMAPT | |
| SCHEMBL19511841 | 0.73 | ITGA4 (0.50) | ESR1ESR2KMT2AMAPT | |
| SCHEMBL16263469 | 0.73 | LMNA (0.48) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL29401352 | 0.73 | LMNA (0.48) | SMN1; SMN2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |