Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PDE4A | P27815 | 9/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876868 | 0.83 | PDE4A (0.44) | KMT2APDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6888521 | 0.77 | CA2 (0.41) | KMT2AMEN1LMNAMAPT | |
| SCHEMBL27435238 | 0.75 | PDE4D (0.51) | KMT2APDE4APDE4BMEN1PDE4D | |
| Hydrochloric Acid SCHEMBL1134115 | 0.74 | PDE4A (0.45) | KMT2APDE4APDE4BMEN1LMNA | |
| SCHEMBL4365529 | 0.74 | PDE4B (0.56) | KMT2APDE4APDE4BMEN1LMNA | |
| SCHEMBL21823418 | 0.73 | FPR2 (0.46) | KMT2APDE4APDE4BMEN1LMNA | |
| SCHEMBL21823724 | 0.73 | ERN1 (0.51) | KMT2APDE4APDE4BMEN1LMNA | |
| SCHEMBL16334372 | 0.72 | NPY1R (0.39) | KMT2APDE4APDE4BLMNAMAPT | |
| SCHEMBL16096941 | 0.72 | POLB (0.40) | KMT2AMEN1MAPT | |
| SCHEMBL2242278 | 0.71 | THRA (0.42) | KMT2APDE4AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749417-A4 | CYANO COMPOUNDS AND PREPARATIONS THEREOF | SMITHKLINE BEECHAM CORP (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0749417-A1 | CYANO COMPOUNDS AND PREPARATIONS THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024381-A1 | CYANO COMPOUNDS AND PREPARATIONS THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-14 | — | — | WO | disclosed |