Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CCR10 | P46092 | 4/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747190 | 0.82 | MMP2 (0.49) | F2CCR10PLAUALDH1A1MAPK1 | |
| SCHEMBL5875648 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2 | |
| SCHEMBL5189435 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2 | |
| SCHEMBL7445799 | 0.76 | PLAU (0.55) | F2PLAU | |
| SCHEMBL27449963 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL22500601 | 0.75 | MMP2 (0.48) | F2SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7441720 | 0.74 | PLAU (0.57) | F2PLAU | |
| SCHEMBL15943456 | 0.74 | CCR10 (0.79) | CCR10PLAUALDH1A1MAPK1 | |
| SCHEMBL4055687 | 0.73 | MMP9 (0.74) | — | |
| SCHEMBL22500340 | 0.73 | MEN1 (0.79) | F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753667-A | ANTITHROMBOSIS | SYNTHELABO (FR) | 1998-05-19 | — | — | US | disclosed |
| US-5753667-A | ANTITHROMBOSIS | SYNTHELABO (FR) | 1998-05-19 | — | — | US | disclosed |
| US-5602149-A | TREATING OR PREVENTING THROMBOSIS | SYNTHELABO (FR) | 1997-02-11 | — | — | US | disclosed |
| US-5602149-A | TREATING OR PREVENTING THROMBOSIS | SYNTHELABO (FR) | 1997-02-11 | — | — | US | disclosed |
| CN-1131153-A | 1-oxy-2-(phenylsulfonamido-) amyl piperidine derivant, its preparation method and medicinal use thereof | SYNTHELABO (FR) | 1996-09-18 | — | — | CN | disclosed |
| EP-0718307-A2 | Derivatives of 1-oxo-2-(phenylsulfonyl-amino)-pentylpiperidine, their preparation and therapeutic use | SYNTHELABO (FR) | 1996-06-26 | — | — | EP | disclosed |
| EP-0718307-A2 | Derivatives of 1-oxo-2-(phenylsulfonyl-amino)-pentylpiperidine, their preparation and therapeutic use | SYNTHELABO (FR) | 1996-06-26 | — | — | EP | disclosed |
| EP-0718307-A2 | Derivatives of 1-oxo-2-(phenylsulfonyl-amino)-pentylpiperidine, their preparation and therapeutic use | SYNTHELABO (FR) | 1996-06-26 | — | — | EP | disclosed |