Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453404 | 0.90 | RORC (0.56) | APEX1RXFP1GAAALDH1A1PTGS1 | |
| SCHEMBL7458372 | 0.89 | APEX1 (0.61) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL7452329 | 0.82 | APEX1 (0.59) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL7445967 | 0.77 | MEN1 (0.64) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL7450804 | 0.76 | MEN1 (0.76) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL7454070 | 0.76 | APEX1 (0.59) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL7458365 | 0.75 | MEN1 (0.64) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL7452313 | 0.75 | MEN1 (0.64) | APEX1RXFP1MEN1KMT2AGAA | |
| SCHEMBL6352305 | 0.75 | SIRT2 (0.60) | ALDH1A1PPARGPPARDPPARANPC1 | |
| SCHEMBL7449698 | 0.74 | APEX1 (0.66) | APEX1MEN1KMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |