Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812108 | 0.83 | MAPK1 (0.57) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL5566305 | 0.83 | ACHE (0.56) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL10697403 | 0.83 | MAPK1 (0.45) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL4589610 | 0.82 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL5473941 | 0.82 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL3844672 | 0.82 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL7049307 | 0.81 | MEN1 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL9512109 | 0.81 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL338196 | 0.80 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL29432883 | 0.80 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391828-A1 | REGULATORS OF CELL DIVISION | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2023-12-07 | — | — | US | claimed |
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | claimed |
| US-11813237-B2 | Creatine, its derivatives, compositions and methods of use thereof | YU RUEY J (US) | 2023-11-14 | — | — | US | claimed |
| EP-4225780-A2 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2023-08-16 | — | — | EP | claimed |
| WO-2023134732-A1 | PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASES WITH HIGH PENETRATION PRODRUGS OF ASPIRIN AND OTHER NSAIDS | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-07-20 | — | — | WO | claimed |
| US-20230218555-A1 | CREATINE, ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE THEREOF | YU RUEY J (US) | 2023-07-13 | — | — | US | claimed |
| US-11642328-B2 | Creatine, its derivatives, compositions and methods of use thereof | YU RUEY J (US) | 2023-05-09 | — | — | US | claimed |
| US-20220401398-A1 | CREATINE, ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE THEREOF | YU RUEY J (US) | 2022-12-22 | — | — | US | claimed |
| WO-2022074072-A2 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-14 | — | — | WO | claimed |
| WO-2021073038-A1 | O-HYDROXYBENZOIC ACID POLYGLYCOL ESTER COMPOUND, AND SYNTHETIC PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 新乡海盈生物科技有限责任公司 | 2021-04-22 | — | — | WO | claimed |
| EP-0024282-A1 | Benzoyl derivatives, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-03-04 | — | — | EP | claimed |
| EP-0023559-A1 | 2-(Perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |
| US-4217445-A | SKIN DISORDERS | FOTOBIO HOLDING AG (CH) | 1980-08-12 | — | — | US | claimed |
| US-4192868-A | ANTIINFLAMMATORY, ANALGESIC | CIBA-GEIGY CORPORATION (US) | 1980-03-11 | — | — | US | claimed |
| US-4072703-A | HUMAN AND VETERINARY MEDICINE | CHIMIE & BIOLOGIE (FR) | 1978-02-07 | — | — | US | claimed |
| US-4060617-A | Esters of the ophyllinylacetic acid | Wulfing, Johann A. (DT) | 1977-11-29 | — | — | US | claimed |
| US-4014997-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1977-03-29 | — | — | US | claimed |
| US-3988446-A | Glycerides with anti-inflammatory properties | ABBOTT LABORATORIES (US) | 1976-10-26 | — | — | US | claimed |
| US-3975532-A | ANALGESIC | ICI UNITED STATES INC. (US) | 1976-08-17 | — | — | US | claimed |
| US-3953596-A | 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals | ICI UNITED STATES INC. (US) | 1976-04-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391828-A1 | REGULATORS OF CELL DIVISION | PCNA, BOD1L1, MKI67 | PTGS2 3273/4885KDM4E 3982/4885HSD17B10 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.