Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448183 | 0.97 | NPC1 (0.36) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7450337 | 0.97 | NPC1 (0.36) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7449129 | 0.95 | RAB9A (0.40) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7448650 | 0.94 | F2 (0.36) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7420823 | 0.94 | F2 (0.36) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7452478 | 0.93 | F2 (0.36) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7448580 | 0.91 | NPC1 (0.37) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7449468 | 0.91 | NPC1 (0.37) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7447557 | 0.90 | ALDH1A1 (0.39) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7419831 | 0.90 | F2 (0.38) | RAB9ANPC1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |