Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448183 | 1.00 | NPC1 (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7446181 | 0.97 | RAB9A (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7420823 | 0.97 | F2 (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7448650 | 0.97 | F2 (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7452478 | 0.96 | F2 (0.36) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7449129 | 0.94 | RAB9A (0.40) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7448580 | 0.90 | NPC1 (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7449468 | 0.90 | NPC1 (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7447557 | 0.89 | ALDH1A1 (0.39) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7453448 | 0.88 | RAB9A (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |