SCHEMBL744622

SCHEMBL744622

COc1ccc(O)c(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.44
HPGD P15428 3/20 0.44
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
ALOX15 P16050 2/20 0.44
ALDH1A1 P00352 4/20 0.44
GAA P10253 1/20 0.44
MAOB P27338 1/20 0.43
HIF1A Q16665 1/20 0.42
EPAS1 Q99814 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PTPN7 P35236 1/20 0.39
DUSP3 P51452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30577021 1.00 TP53 (0.44) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL2955217 0.86 CA2 (0.43) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL1054064 0.85 HIF1A (0.50) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL14840363 0.84 ESR1 (0.41) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL784918 0.83 ALDH1A1 (0.41) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL785146 0.83 ALDH1A1 (0.41) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL3641637 0.82 ALDH1A1 (0.41) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL2044785 0.82 ALDH1A1 (0.41) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL31049564 0.81 MAPT (0.59) TP53HPGDLMNACYP3A4ALOX15
SCHEMBL5760161 0.81 ALDH1A1 (0.34) TP53HPGDLMNACYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4382588-A1 ADDITIVES FOR IMPROVING THERMAL STABILITY OF FUELS BASF SE (DE) 2024-06-12 EP claimed
EP-2914602-B1 PROCESS FOR THE PREPARATION OF ISOHEXIDES WITH AN IMPROVED PURITY AND COLOUR STABILITY ARCHER DANIELS MIDLAND CO (US) 2019-09-18 EP claimed
CN-106554244-A For the high temperature modification compound polymerization inhibitor in aromatic olefin monomers distillation process and its application 中国石油化工股份有限公司 2017-04-05 CN claimed
US-9266900-B2 Additives for improved isohexide products ARCHER DANIELS MIDLAND COMPANY (US) 2016-02-23 US claimed
US-20150274746-A1 ADDITIVES FOR IMPROVED ISOHEXIDE PRODUCTS ARCHER DANIELS MIDLAND COMPANY 2015-10-01 US claimed
WO-2014174106-A1 VACUUM PUMP OIL SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2014-10-30 WO claimed
US-8241855-B2 Method for detecting cytosine methylations EPIGENOMICS AG (DE) 2012-08-14 US claimed
CN-101240128-B Method for reducing odor in latex paints ROHM & HAAS 2012-06-27 CN claimed
CN-102070394-A Scale inhibitor for styrene rectification system ZHEJIANG HUANGHUA TECHNOLOGY CO LTD 2011-05-25 CN claimed
US-7560205-B2 Photoconductive imaging members XEROX CORPORATION (US) 2009-07-14 US claimed
EP-1325154-A2 METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS Epigenomics AG (DE) 2003-07-09 EP claimed
EP-1321136-A1 Cosmetic compositions of powder-type containing anti-wrinkling ingredients Coreana Cosmetics Co., Ltd. (KR) 2003-06-25 EP claimed
EP-1319387-A2 Cosmetic compositions of powder-type containing whitening ingredient Coreana Cosmetics Co., Ltd. (KR) 2003-06-18 EP claimed
EP-1294945-A2 METHOD FOR DETECTING CYTOSINE METHYLATIONS Epigenomics AG (DE) 2003-03-26 EP claimed
US-6376209-B2 HEAT TREATMENT DADE BEHRING MARBURG GMBH (DE) 2002-04-23 US claimed
WO-2002031186-A2 METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2002-04-18 WO claimed
WO-2001098528-A2 METHOD FOR DETECTING CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2001-12-27 WO claimed
EP-0769016-B1 PROCESS FOR PRODUCING LIGHT-COLOURED SURFACTANTS HENKEL KGAA (DE) 1998-09-30 EP claimed
US-5461080-A Using vapor phase antioxidant VYREX CORPORATION (US) 1995-10-24 US claimed
EP-0177137-A2 White blood cell differentiation composition and method Bayer Corporation (US) 1986-04-09 EP claimed