SCHEMBL784918

SCHEMBL784918

COc1ccc(O)c(C)c1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
GAA P10253 1/20 0.41
TP53 P04637 3/20 0.41
HPGD P15428 3/20 0.41
LMNA P02545 2/20 0.41
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 2/20 0.41
MAOB P27338 1/20 0.41
HIF1A Q16665 1/20 0.40
EPAS1 Q99814 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TSHR P16473 1/20 0.39
TUBB1 Q9H4B7 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14840363 0.85 ESR1 (0.41) ALDH1A1GAATP53HPGDLMNA
SCHEMBL785146 0.84 ALDH1A1 (0.41) ALDH1A1GAATP53HPGDLMNA
SCHEMBL744622 0.83 TP53 (0.44) ALDH1A1GAATP53HPGDLMNA
SCHEMBL30577021 0.83 TP53 (0.44) ALDH1A1GAATP53HPGDLMNA
SCHEMBL1054064 0.82 HIF1A (0.50) ALDH1A1GAATP53HPGDLMNA
SCHEMBL19695748 0.79 ATM (0.38) ALDH1A1GAAHPGDLMNAALOX15
SCHEMBL2044785 0.78 ALDH1A1 (0.41) ALDH1A1GAATP53HPGDLMNA
SCHEMBL4483852 0.78 TRPA1 (0.44) ALDH1A1GAATP53HPGDLMNA
SCHEMBL2955217 0.78 CA2 (0.43) ALDH1A1GAATP53HPGDLMNA
SCHEMBL70459 0.76 ESR1 (0.49) ALDH1A1TP53HPGDLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3819301-B1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP SHINETSU CHEMICAL CO (JP) 2025-08-06 EP disclosed
US-12371447-B2 Method for producing (meth)acryloxy group-containing organosilicon compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-07-29 US disclosed
EP-4174076-B1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHINETSU CHEMICAL CO (JP) 2024-07-24 EP disclosed
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
EP-4174076-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-05-03 EP disclosed
CN-116041382-A Method for producing organosilicon compounds containing (meth) acryloxy groups 信越化学工业株式会社 2023-05-02 CN disclosed
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-05 US disclosed
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-13 US disclosed
EP-3819301-A1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP Shin-Etsu Chemical Co., Ltd. (JP) 2021-05-12 EP disclosed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-7601378-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-10-13 US disclosed
US-7595074-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-09-29 US disclosed
US-7507454-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-03-24 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070154430-A1 Polymeric antioxidants MASSACHUSETTS LOWELL, UNIVERSITY OF 2007-07-05 US disclosed
US-20070154608-A1 Antioxidant preservatives to increase the shelf life and palatability of lipid-containing foods and other products containing moieties (e.g., unsaturated carbon-carbon bonds) that can be damaged by free radicals; hydroxy substituted benzene polymers UNIVERSITY OF MASSACHUSETTS LOWELL 2007-07-05 US disclosed
US-20070154720-A1 Polymeric antioxidants CHOLLI ASHOK L 2007-07-05 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-7223432-B2 Polymeric antioxidants University of Massachusettes Lowell (US) 2007-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154430-A1 Polymeric antioxidants GPX4, NQO1, LPO ALDH1A1 287/4885GAA 2526/4885TP53 3247/4885
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR ALDH1A1 2631/4885GAA 3708/4885TP53 3831/4885
US-12371447-B2 Method for producing (meth)acryloxy group-containing organosilicon compounds HM13, RPS13, GRHPR ALDH1A1 1759/4885GAA 4202/4885TP53 3877/4885
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR ALDH1A1 2744/4885GAA 3730/4885TP53 3906/4885
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS HM13, RPS13, GRHPR ALDH1A1 1759/4885GAA 4202/4885TP53 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.