Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.60 |
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | FPR1 | P21462 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444870 | 0.89 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7413110 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7075515 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7455081 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7447973 | 0.86 | ITGB3 (0.81) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| Acetic Acid SCHEMBL7418342 | 0.86 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7445984 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL8093675 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| Hydrochloric Acid SCHEMBL7447955 | 0.86 | ITGB3 (0.80) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7450405 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BFPR2FPR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |