Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463085 | 0.93 | ITGB3 (0.44) | ITGB3ITGA2BSTSMMP1MMP9 | |
| SCHEMBL7445250 | 0.92 | L3MBTL1 (0.43) | ITGB3ITGA2BSTSMMP1MMP3 | |
| SCHEMBL7455702 | 0.90 | ITGB3 (0.46) | ITGB3ITGA2BSTSGPR119MAPK1 | |
| SCHEMBL7443409 | 0.90 | ITGB3 (0.45) | ITGB3ITGA2BSTSALDH1A1NPC1 | |
| SCHEMBL7440088 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BALDH1A1HPGDMAPT | |
| SCHEMBL7447910 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BF2R | |
| SCHEMBL7443488 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BALDH1A1HPGDMAPT | |
| SCHEMBL7446367 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BSTSMAPK1KDM4E | |
| SCHEMBL7501790 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BF2R | |
| SCHEMBL7450244 | 0.85 | KMT2A (0.45) | ITGB3ITGA2BSTSMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |