Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL11557822 | 0.91 | OPRM1 (0.36) | TSHRDNM1MEN1THRBHTT | |
| SCHEMBL4540450 | 0.84 | DNM1 (0.45) | TSHRCYP3A4DNM1THRBALDH1A1 | |
| SCHEMBL27574241 | 0.81 | DNM1 (0.43) | TSHRCYP3A4DNM1THRBALDH1A1 | |
| SCHEMBL7446402 | 0.80 | TSHR (0.37) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL2854096 | 0.78 | DNM1 (0.48) | TSHRDNM1THRBALDH1A1CA2 | |
| SCHEMBL13451749 | 0.78 | DNM1 (0.48) | TSHRDNM1THRBALDH1A1CA2 | |
| SCHEMBL4434367 | 0.78 | — | — | |
| SCHEMBL27489781 | 0.78 | DNM1 (0.33) | CYP3A4DNM1ALDH1A1TDP1CA1 | |
| SCHEMBL11719502 | 0.77 | CYP3A4 (0.36) | TSHRCYP3A4DNM1ALDH1A1TDP1 | |
| SCHEMBL14964602 | 0.76 | DNM1 (0.52) | TSHRDNM1THRBALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047599-A1 | SUCCINAMIDE DERIVATIVES USEFUL AS TNF- AND/OR MMP INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-18 | — | — | WO | disclosed |