SCHEMBL7446402

SCHEMBL7446402

CCCC(Cl)CCCOCCCC(Cl)CCC

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
CYP3A4 P08684 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3798937 0.81 TSHR (0.30) TSHR
SCHEMBL7446394 0.80 TSHR (0.37) TSHRMEN1THRBHTTKMT2A
SCHEMBL2577273 0.78
SCHEMBL4434367 0.78
SCHEMBL6703853 0.78
Potassium SCHEMBL11557822 0.76 OPRM1 (0.36) TSHRMEN1THRBHTTKMT2A
SCHEMBL18866502 0.76 HTT (0.37) TSHRMEN1THRBHTTKMT2A
SCHEMBL1784504 0.76
SCHEMBL3602893 0.76 OPRM1 (0.43) TSHRTHRB
SCHEMBL25225166 0.75 ALDH1A1 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997047599-A1 SUCCINAMIDE DERIVATIVES USEFUL AS TNF- AND/OR MMP INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-12-18 WO disclosed