SCHEMBL7446499

SCHEMBL7446499

O=C(O)COc1cncnc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.54
ALDH1A1 P00352 3/20 0.46
PTPN7 P35236 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
FFAR1 O14842 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.43
PTPN12 Q05209 1/20 0.43
LMNA P02545 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
TBXAS1 P24557 3/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 1/20 0.41
NR4A1 P22736 1/20 0.41
APEX1 P27695 1/20 0.41
MCL1 Q07820 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23321188 0.77 ALOX15 (0.52) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL22711544 0.77 ALOX15 (0.52) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL2009003 0.76 ALOX15 (0.62) ALOX15PTPN7FFAR1MAPTLMNA
Hydrochloric Acid SCHEMBL6067927 0.75 ALOX15 (0.60) ALOX15KMT2AMAPTLMNA
SCHEMBL14599861 0.75 HCAR2 (0.47) ALOX15PTPN7SMN1; SMN2FFAR1LMNA
Hydrochloric Acid SCHEMBL29642862 0.75 ALOX15 (0.60) ALOX15KMT2AMAPTLMNA
SCHEMBL2841832 0.75 CHRNB2 (0.50) ALOX15HCAR2MCL1
SCHEMBL21328699 0.75 LDHA (0.49) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL29416512 0.75 LDHA (0.49) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL7425169 0.74 ALOX15 (0.65) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108350485-A Multiplex amplification detection assay and separation and detection of plasma DNA 精密科学发展有限责任公司 2018-07-31 CN disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 US disclosed
EP-0876353-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS Abbott Laboratories (US) 1998-11-11 EP disclosed
WO-1997021683-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1997-06-19 WO disclosed