Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.71 |
| ▸ | CTSS | P25774 | 8/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433454 | 0.88 | CTSK (0.55) | CTSKCTSSCTSBCTSLPPARA | |
| SCHEMBL7435956 | 0.88 | CTSK (0.55) | CTSKCTSSCTSBCTSLPPARA | |
| SCHEMBL7443191 | 0.86 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL7440842 | 0.85 | CTSK (0.53) | CTSKCTSSPPARAPPARG | |
| SCHEMBL7449272 | 0.84 | CTSK (0.52) | CTSKCTSSPPARAPPARG | |
| SCHEMBL7446907 | 0.82 | CTSK (0.56) | CTSKCTSSCTSBCTSLPPARA | |
| SCHEMBL7437012 | 0.81 | CTSK (0.71) | CTSKCTSSCTSBCTSL | |
| SCHEMBL29771292 | 0.80 | PPARA (0.56) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL18248042 | 0.80 | PPARA (0.56) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL7430637 | 0.80 | CTSK (0.56) | CTSKCTSSCTSBCTSLPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |