Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442582 | 0.88 | CTSK (0.46) | CTSKGABRB1GABRB2CTSBCTSS | |
| SCHEMBL7437012 | 0.87 | CTSK (0.71) | CTSKCTSBCTSSCTSLCTSH | |
| SCHEMBL13715427 | 0.82 | MMP9 (0.59) | CTSKMMP9GABRB1GABRB2CTSB | |
| SCHEMBL7430555 | 0.81 | METAP2 (0.47) | CTSKMMP9GABRB1GABRB2CTSB | |
| SCHEMBL7446907 | 0.79 | CTSK (0.56) | CTSKGABRB1GABRB2CTSBCTSS | |
| SCHEMBL7447101 | 0.79 | CTSK (0.56) | CTSKGABRB1GABRB2CTSBCTSS | |
| SCHEMBL7447637 | 0.79 | CTSK (0.52) | CTSKGABRB1GABRB2CTSBCTSS | |
| SCHEMBL7439368 | 0.77 | CTSK (0.56) | CTSKGABRB1GABRB2CTSBCTSS | |
| SCHEMBL7430637 | 0.77 | CTSK (0.56) | CTSKGABRB1GABRB2CTSBCTSS | |
| SCHEMBL7443211 | 0.77 | MMP9 (0.47) | CTSKMMP9GABRB1GABRB2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |