Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 7/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 4/20 | 0.35 |
| ▸ | FPR2 | P25090 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410295 | 0.82 | LMNA (0.39) | DPP7DPP4 | |
| SCHEMBL7415541 | 0.76 | F2 (0.48) | CFD | |
| SCHEMBL7450500 | 0.71 | MLLT1 (0.39) | MLLT1DGAT2 | |
| SCHEMBL7446447 | 0.71 | F2 (0.40) | MLLT1PARP1PARP2DGAT2 | |
| SCHEMBL7447141 | 0.70 | MLLT1 (0.37) | MLLT1DPP7 | |
| SCHEMBL7421110 | 0.70 | MLLT1 (0.38) | MLLT1DGAT2 | |
| SCHEMBL7447512 | 0.69 | MLLT1 (0.37) | MLLT1DGAT2 | |
| SCHEMBL7556081 | 0.69 | DGAT2 (0.38) | MLLT1PARP1PARP2DGAT2 | |
| SCHEMBL7445649 | 0.69 | MLLT1 (0.37) | MLLT1DGAT2 | |
| SCHEMBL6457229 | 0.69 | F2 (0.41) | MLLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |