SCHEMBL7447157

SCHEMBL7447157

CCCCOC(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 13/20 0.51
NAALAD2 Q9Y3Q0 2/20 0.51
RIMKLA Q8IXN7 1/20 0.51
ITGB3 P05106 2/20 0.48
ITGA2B P08514 2/20 0.48
NOD1 Q9Y239 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16124669 0.95 NOD1 (0.51) FOLH1NAALAD2RIMKLAITGB3ITGA2B
SCHEMBL10036530 0.94 NOD1 (0.53) FOLH1NAALAD2RIMKLANOD1
SCHEMBL16124659 0.94 NOD1 (0.53) FOLH1NAALAD2RIMKLANOD1
SCHEMBL1387945 0.90 FOLH1 (0.55) FOLH1NAALAD2RIMKLANOD1
SCHEMBL1387645 0.90 FOLH1 (0.55) FOLH1NAALAD2RIMKLANOD1
SCHEMBL1387643 0.90 FOLH1 (0.55) FOLH1NAALAD2RIMKLANOD1
SCHEMBL284211 0.89 ITGB3 (0.46) ITGB3ITGA2BNOD1
SCHEMBL1077922 0.89 NOD1 (0.48) ITGB3ITGA2BNOD1
SCHEMBL3655323 0.89 ITGB3 (0.46) ITGB3ITGA2BNOD1
SCHEMBL7382637 0.89 NOD1 (0.48) ITGB3ITGA2BNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722438-A1 HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-07-24 EP disclosed
WO-1995009841-A1 HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-04-13 WO disclosed