Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.50 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036530 | 0.98 | NOD1 (0.53) | NOD1FOLH1RIMKLANAALAD2PLA2G2C | |
| SCHEMBL16124659 | 0.98 | NOD1 (0.53) | NOD1FOLH1RIMKLANAALAD2PLA2G2C | |
| SCHEMBL7447157 | 0.95 | FOLH1 (0.51) | NOD1FOLH1RIMKLANAALAD2ITGB3 | |
| SCHEMBL1387645 | 0.89 | FOLH1 (0.55) | NOD1FOLH1RIMKLANAALAD2 | |
| SCHEMBL1387945 | 0.89 | FOLH1 (0.55) | NOD1FOLH1RIMKLANAALAD2 | |
| SCHEMBL1387643 | 0.89 | FOLH1 (0.55) | NOD1FOLH1RIMKLANAALAD2 | |
| SCHEMBL8973585 | 0.88 | NOD1 (0.55) | NOD1EPHX1 | |
| SCHEMBL3625936 | 0.86 | NOD1 (0.50) | NOD1EPHX1ITGB3ITGA2B | |
| SCHEMBL3629433 | 0.84 | NOD1 (0.53) | NOD1EPHX1 | |
| SCHEMBL3655323 | 0.84 | ITGB3 (0.46) | NOD1EPHX1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NOD1 1456/4885FOLH1 2389/4885RIMKLA 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.