SCHEMBL7447258

SCHEMBL7447258

CC(C)(F)C(C(=O)CNC(=O)Cn1c(-c2ccccc2)ccc(NS(=O)(=O)O)c1=O)(C(C)(C)F)C(C)(C)F.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7314760 0.82 ELANE (0.58) ELANE
SCHEMBL9011872 0.77 ELANE (0.84) ELANE
SCHEMBL9011835 0.75 ELANE (0.67) ELANE
SCHEMBL5076881 0.68 ELANE (1.00) ELANE
SCHEMBL7447265 0.67 ELANE (0.83) ELANE
SCHEMBL6132131 0.67 ELANE (1.00) ELANE
SCHEMBL9013191 0.66 ELANE (0.50) ELANE
SCHEMBL7441714 0.64 ELANE (0.79) ELANE
SCHEMBL7314776 0.64 ELANE (0.61) ELANE
SCHEMBL7436613 0.64 ELANE (0.89) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993021212-A1 LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY ZENECA LIMITED (GB) 1993-10-28 WO disclosed