Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.58 |
| ▸ | CTRC | Q99895 | 4/20 | 0.40 |
| ▸ | CMA1 | P23946 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314776 | 0.81 | ELANE (0.61) | ELANECTRC | |
| SCHEMBL7274007 | 0.77 | ELANE (0.54) | ELANECTRCCMA1 | |
| SCHEMBL7274370 | 0.74 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL4452759 | 0.73 | ALDH1A1 (0.59) | ELANE | |
| SCHEMBL8647999 | 0.73 | KDM4E (0.62) | ELANE | |
| SCHEMBL6556265 | 0.72 | ELANE (0.71) | ELANECTRCCMA1 | |
| SCHEMBL7281923 | 0.71 | ELANE (0.59) | ELANECTRCCMA1 | |
| SCHEMBL9111284 | 0.71 | CTRC (0.53) | ELANECTRCCMA1 | |
| SCHEMBL7552480 | 0.70 | ELANE (0.64) | ELANECTRCCMA1 | |
| SCHEMBL8536723 | 0.70 | ELANE (0.78) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | claimed |