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Sugi Predict / Compounds / SCHEMBL9011835

SCHEMBL9011835

SCHEMBL9011835

CC(C)(F)C(C(=O)CNC(=O)Cn1c(-c2ccc(C(=O)O)cc2)ccc(NC(=O)OCc2ccccc2)c1=O)(C(C)(C)F)C(C)(C)F

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 20/20 0.67
▸ CTRC Q99895 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011841 0.85 ELANE (0.68) ELANECTRC
SCHEMBL7284500 0.80 ELANE (1.00) ELANECTRC
SCHEMBL6556311 0.77 ELANE (0.79) ELANECTRC
SCHEMBL7273831 0.77 ELANE (1.00) ELANECTRC
SCHEMBL7447258 0.75 ELANE (0.51) ELANE
SCHEMBL7276488 0.74 ELANE (0.64) ELANECTRC
SCHEMBL7314760 0.74 ELANE (0.58) ELANECTRC
SCHEMBL8536676 0.74 ELANE (0.59) ELANECTRC
SCHEMBL7276733 0.74 ELANE (0.88) ELANECTRC
SCHEMBL7284339 0.74 ELANE (0.80) ELANECTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521179-A Heterocyclic amides ZENECA LIMITED (GB) 1996-05-28 — — US disclosed