Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 6/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD5 | P21918 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447444 | 0.87 | LTA4H (0.54) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL6961322 | 0.79 | HRH1 (0.51) | LTA4HTSHRHRH1DRD1DRD4 | |
| SCHEMBL7447035 | 0.79 | PSMB1 (0.64) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL6958135 | 0.78 | TDP1 (0.49) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL6957964 | 0.77 | LTA4H (0.45) | LTA4HTSHRHRH1DRD1DRD4 | |
| SCHEMBL7348634 | 0.75 | PSMB1 (0.55) | LTA4HHRH3 | |
| SCHEMBL6963357 | 0.73 | TDP1 (0.44) | LTA4HTSHRDRD1DRD3DRD2 | |
| SCHEMBL7346727 | 0.73 | LTA4H (0.46) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL6963616 | 0.73 | LTA4H (0.52) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL23038800 | 0.73 | TSHR (0.61) | LTA4HTSHRHRH1DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |