Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401263 | 1.00 | SIGMAR1 (0.56) | SIGMAR1HTR7ALDH1A1BLMKDM4E | |
| SCHEMBL7399289 | 1.00 | SIGMAR1 (0.56) | SIGMAR1HTR7ALDH1A1BLMKDM4E | |
| SCHEMBL7404241 | 0.96 | ALDH1A1 (0.57) | SIGMAR1HTR7ALDH1A1BLMKDM4E | |
| SCHEMBL7401091 | 0.96 | ALDH1A1 (0.57) | SIGMAR1HTR7ALDH1A1BLMKDM4E | |
| SCHEMBL7404627 | 0.89 | HTR7 (0.55) | SIGMAR1HTR7ALDH1A1KDM4E | |
| SCHEMBL7400983 | 0.89 | HTR7 (0.55) | SIGMAR1HTR7ALDH1A1KDM4E | |
| SCHEMBL7408920 | 0.86 | SIGMAR1 (0.72) | SIGMAR1KMT2A | |
| SCHEMBL7400077 | 0.86 | SIGMAR1 (0.72) | SIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL7404498 | 0.84 | SIGMAR1 (0.70) | SIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL7450136 | 0.84 | SIGMAR1 (0.70) | SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024390-A1 | NOVEL PHENYL(-ALKYL/ALKOXY)-1-AMINOALKYL-SUBSTITUTED PIPERIDINES AND PYRROLIDINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-09-14 | — | — | WO | disclosed |