Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | MMP12 | P39900 | 3/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275003 | 0.80 | TSHR (0.50) | L3MBTL1NSD2ABL1PPARGRIN1 | |
| SCHEMBL10959391 | 0.75 | NOTUM (0.61) | MMP1MMP2MMP12MMP9L3MBTL1 | |
| SCHEMBL2797645 | 0.74 | SRD5A2 (0.60) | MMP1MMP2MMP12MMP9L3MBTL1 | |
| SCHEMBL16910470 | 0.71 | KDM4C (0.49) | MMP1MMP2MMP12MMP9L3MBTL1 | |
| SCHEMBL3320062 | 0.71 | L3MBTL1 (0.47) | L3MBTL1NSD2ABL1PPARGRIN1 | |
| SCHEMBL12313404 | 0.70 | MAPT (0.47) | MMP1MMP2MMP12MMP9L3MBTL1 | |
| Charcoal, Activated SCHEMBL30421850 | 0.69 | MAPT (0.46) | MMP1MMP2MMP12MMP9L3MBTL1 | |
| SCHEMBL22959481 | 0.69 | MMP1 (1.00) | MMP1MMP2MMP12MMP9 | |
| SCHEMBL2796820 | 0.68 | CTSV (0.56) | L3MBTL1NSD2ABL1PPARGRIN1 | |
| SCHEMBL17459262 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047299-A1 | AMIDINO AND GUANIDINO HETEROCYCLIC PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |