Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186774 | 0.74 | SMN1; SMN2 (0.46) | OPRM1OPRD1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3312757 | 0.73 | SMN1; SMN2 (0.58) | OPRM1OPRD1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL18889556 | 0.72 | OPRM1 (0.60) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28845914 | 0.71 | SMN1; SMN2 (0.49) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14230942 | 0.71 | SMN1; SMN2 (0.38) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10558801 | 0.70 | OPRM1 (0.51) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18112755 | 0.70 | OPRM1 (0.43) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4541997 | 0.70 | KCNA5 (0.48) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8740951 | 0.70 | SMN1; SMN2 (0.66) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9681172 | 0.69 | SMN1; SMN2 (0.50) | OPRM1OPRD1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813527-A4 | 6-SUBSTITUTED PYRAZOLO 3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF | SANOFI WINTHROP INC (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0813527-A1 | 6-SUBSTITUTED PYRAZOLO 3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF | SANOFI PHARMACEUTICALS, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028429-A1 | 6-SUBSTITUTED PYRAZOLO [3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-09-19 | — | — | WO | disclosed |