Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370017 | 0.88 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL8477824 | 0.88 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL13832427 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL8325689 | 0.82 | CA12 (0.48) | ALDH1A1POLB | |
| SCHEMBL5161545 | 0.81 | CYP1A2 (0.52) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL4199641 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL79068 | 0.80 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL38654784 | 0.80 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL8663606 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL3576370 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912182-A4 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912182-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| WO-1998000144-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |