Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370017 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL13832427 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL7447972 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8477824 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL709158 | 0.77 | POLB (0.50) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL10788442 | 0.77 | TTR (0.49) | ALDH1A1PPARAMEN1KMT2AMAPT | |
| SCHEMBL395184 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTPRMT1 | |
| SCHEMBL5910982 | 0.76 | ALDH3A1 (0.47) | ALDH1A1PPARAMEN1KMT2AMAPT | |
| SCHEMBL5910980 | 0.76 | ALDH3A1 (0.47) | ALDH1A1PPARAMEN1KMT2AMAPT | |
| SCHEMBL7447401 | 0.76 | ALDH1A1 (0.44) | ALDH1A1PPARAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |