Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161321 | 0.89 | ALDH1A1 (0.46) | CYP1A2ALDH1A1CYP17A1NPC1LMNA | |
| SCHEMBL23164348 | 0.89 | ALDH1A1 (0.48) | CYP1A2ALDH1A1CYP17A1NPC1LMNA | |
| SCHEMBL395184 | 0.86 | ALDH1A1 (0.50) | CYP1A2ALDH1A1CYP17A1NPC1LMNA | |
| SCHEMBL15649506 | 0.84 | ALDH1A1 (0.46) | CYP1A2ALDH1A1CYP17A1NPC1LMNA | |
| SCHEMBL3576370 | 0.81 | ALDH1A1 (0.46) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL7447972 | 0.81 | ALDH1A1 (0.53) | ALDH1A1NPC1MAPTRAB9AMEN1 | |
| SCHEMBL7448057 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL1697905 | 0.81 | RAB9A (0.61) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL1181428 | 0.80 | MEN1 (0.58) | CYP1A2ALDH1A1NPC1LMNAMAPT | |
| SCHEMBL22897658 | 0.80 | MAPT (0.49) | ALDH1A1NPC1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | CYP1A2 660/4885ALDH1A1 12/4885PTGDR2 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.