Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13969591 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ASMN1; SMN2PKM | |
| SCHEMBL12658621 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2PKM | |
| SCHEMBL4569783 | 0.77 | MAPT (0.58) | ALDH1A1MAPTPKMGAA | |
| SCHEMBL29910923 | 0.77 | MAPT (0.58) | ALDH1A1MAPTPKMGAA | |
| SCHEMBL265030 | 0.74 | MAPT (0.48) | ALDH1A1MAPTKMT2ASMN1; SMN2PKM | |
| SCHEMBL12659017 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2PKM | |
| SCHEMBL7428387 | 0.73 | MAPT (0.45) | ALDH1A1MAPTPKMGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL265008 | 0.73 | GAA (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2PKM | |
| SCHEMBL18500486 | 0.73 | PKM (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2PKM | |
| SCHEMBL6058476 | 0.72 | L3MBTL1 (0.38) | ALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000454-A1 | BENZIMIDAZOLE COMPOUNDS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |