Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7448707 | 0.89 | NQO2 (0.40) | POLBMAPTMEN1GAAKMT2A | |
| SCHEMBL7445637 | 0.85 | ALDH1A1 (0.39) | POLBMAPTMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL7447297 | 0.78 | POLB (0.41) | POLBMAPTMEN1GAAKMT2A | |
| SCHEMBL7452770 | 0.77 | HCRTR1 (0.34) | MAPTMEN1GAAKMT2AHCRTR1 | |
| Hydrochloric Acid SCHEMBL7446278 | 0.76 | NQO2 (0.39) | POLBMAPTMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL7444749 | 0.76 | NQO2 (0.47) | POLBMAPTNQO2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7447354 | 0.75 | NQO2 (0.38) | POLBMAPTMEN1GAAKMT2A | |
| SCHEMBL7442527 | 0.74 | POLB (0.41) | POLBMAPTMEN1GAAKMT2A | |
| SCHEMBL7444335 | 0.74 | MAPT (0.41) | POLBMAPTMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL7445558 | 0.72 | SMN1; SMN2 (0.40) | POLBMEN1GAAKMT2ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | disclosed |