Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445637 | 0.89 | ALDH1A1 (0.39) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7442527 | 0.88 | POLB (0.41) | MAPTALDH1A1LMNAPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7447454 | 0.86 | KLK1 (0.44) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7452192 | 0.85 | NPC1 (0.34) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7394949 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7451792 | 0.81 | IDH1 (0.39) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7441087 | 0.81 | SMN1; SMN2 (0.35) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7448859 | 0.79 | MAPT (0.42) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL7448750 | 0.79 | PDE2A (0.36) | MAPTALDH1A1LMNANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL7161775 | 0.79 | NQO2 (0.45) | MAPTALDH1A1LMNANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | disclosed |