Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488869 | 0.83 | MAPT (0.42) | SMN1; SMN2MAPTHTTLMNAKDM4E | |
| SCHEMBL5227781 | 0.81 | MAPT (0.40) | SMN1; SMN2MAPTHTTLMNAKDM4E | |
| SCHEMBL6678662 | 0.79 | MAPT (0.39) | SMN1; SMN2MAPTHTTLMNAKDM4E | |
| SCHEMBL15617562 | 0.78 | MAPT (0.46) | SMN1; SMN2MAPTHTTLMNAKDM4E | |
| SCHEMBL5231955 | 0.73 | MEN1 (0.51) | SMN1; SMN2MAPTLMNAKDM4EMEN1 | |
| SCHEMBL9574960 | 0.73 | DAO (0.41) | SMN1; SMN2MAPTLMNAKDM4EGAA | |
| SCHEMBL1483376 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2MAPTHTTLMNAMEN1 | |
| SCHEMBL5229628 | 0.72 | SLC9A1 (0.53) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL27297730 | 0.72 | MAPT (0.37) | SMN1; SMN2MAPTHTTLMNAKDM4E | |
| SCHEMBL17630168 | 0.72 | KDM4E (0.37) | SMN1; SMN2MAPTHTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173468-A1 | INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066618-A1 | INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-09 | — | — | WO | disclosed |