Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230549 | 0.86 | SLC9A1 (0.52) | SLC9A1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5231955 | 0.82 | MEN1 (0.51) | SLC9A1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5231463 | 0.80 | SLC9A1 (0.47) | SLC9A1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL829093 | 0.80 | SLC9A1 (0.61) | SLC9A1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8187301 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNA | |
| SCHEMBL5202332 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL5231561 | 0.74 | SMN1; SMN2 (0.62) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL5198179 | 0.73 | HDAC3 (0.49) | SLC9A1LMNARAB9AHDAC3HDAC4 | |
| SCHEMBL2893474 | 0.73 | SLC9A1 (0.67) | SLC9A1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7448258 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1MEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461335-B1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1461335-A1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | Bayer HealthCare AG (DE) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003055878-A1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |