Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009812 | 0.85 | NPC1 (0.53) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7445464 | 0.82 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7268397 | 0.80 | NPC1 (0.53) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8644740 | 0.79 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1MAPTHPGD | |
| SCHEMBL6900506 | 0.78 | ALDH1A1 (0.51) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL22970829 | 0.78 | ALDH1A1 (0.51) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL11681830 | 0.77 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL25132758 | 0.76 | ALDH1A1 (0.49) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL31072137 | 0.76 | ALDH1A1 (0.49) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL23643807 | 0.76 | ALDH1A1 (0.58) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| US-5726192-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |