Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268397 | 0.88 | NPC1 (0.53) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7445464 | 0.87 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL13260888 | 0.86 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1KMT2AHTT | |
| SCHEMBL7448281 | 0.85 | RAB9A (0.47) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL22970829 | 0.84 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL11681830 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL23643807 | 0.81 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL21107863 | 0.81 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL25132758 | 0.81 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL31072137 | 0.81 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| US-5726192-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |