Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531939 | 0.82 | ELANE (0.57) | ELANECTRB1 | |
| SCHEMBL7831962 | 0.82 | CTRB1 (0.42) | ELANENPC1RAB9ACTRB1KMT2A | |
| SCHEMBL7448303 | 0.81 | ELANE (0.38) | ELANENPC1RAB9AKMT2AFKBP1A | |
| SCHEMBL6809994 | 0.81 | CTRB1 (0.38) | ELANENPC1RAB9ACTRB1KMT2A | |
| SCHEMBL8654536 | 0.81 | ELANE (0.41) | ELANECTRB1SMN1; SMN2 | |
| SCHEMBL6498024 | 0.78 | ELANE (0.37) | ELANENPC1RAB9ACTRB1KMT2A | |
| SCHEMBL7842073 | 0.77 | CTRB1 (0.47) | ELANENPC1RAB9ACTRB1KMT2A | |
| SCHEMBL7840950 | 0.76 | CTRB1 (0.43) | ELANENPC1RAB9ACTRB1KMT2A | |
| SCHEMBL27364609 | 0.76 | ELANE (0.58) | ELANECTRB1 | |
| SCHEMBL7451745 | 0.75 | ELANE (0.43) | ELANENPC1RAB9ACTRB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |