Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 12/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831962 | 0.94 | CTRB1 (0.42) | CTRB1ELANEKMT2ANPC1RAB9A | |
| SCHEMBL7451745 | 0.91 | ELANE (0.43) | CTRB1ELANECALCRLKMT2ANPC1 | |
| SCHEMBL7842073 | 0.89 | CTRB1 (0.47) | CTRB1ELANECALCRLKMT2ANPC1 | |
| SCHEMBL6799137 | 0.87 | CTRB1 (0.39) | CTRB1ELANECALCRLKMT2ANPC1 | |
| SCHEMBL6500697 | 0.85 | LMNA (0.40) | CTRB1ELANEKMT2ATSHR | |
| SCHEMBL27364609 | 0.84 | ELANE (0.58) | CTRB1ELANE | |
| SCHEMBL7845411 | 0.82 | ELANE (0.46) | CTRB1ELANE | |
| SCHEMBL6498129 | 0.81 | ELANE (0.44) | CTRB1ELANENPC1 | |
| SCHEMBL7840487 | 0.81 | CTRB1 (0.53) | CTRB1ELANEKMT2A | |
| SCHEMBL6809994 | 0.81 | CTRB1 (0.38) | CTRB1ELANEKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | claimed |