SCHEMBL7448891

SCHEMBL7448891

Cn1cc(NC(=O)O)c2ccc(OCc3ccccc3)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.48
NPC1 O15118 5/20 0.46
RAB9A P51151 4/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAOB P27338 3/20 0.46
CASP3 P42574 2/20 0.46
SENP8 Q96LD8 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
MAOA P21397 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTR3A P46098 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
PPARG P37231 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
ACHE P22303 1/20 0.44
IMPDH2 P12268 1/20 0.44
CNR1 P21554 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2433126 0.81 LTB4R (0.55) SRD5A2MEN1KMT2AMAOBSMN1; SMN2
SCHEMBL2434205 0.81 NR4A2 (0.58) SRD5A2NPC1RAB9AMAOBSMN1; SMN2
SCHEMBL27732143 0.80 CNR1 (0.49) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL6021902 0.79 PPARG (0.50) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL2085650 0.79 CNR1 (0.47) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL27696946 0.79 SRD5A2 (0.48) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL8305123 0.78 HTR3A (0.54) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL7497382 0.78 CNR1 (0.48) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL15323201 0.77 LTB4R (0.56) SRD5A2NPC1RAB9AMEN1KMT2A
SCHEMBL15323203 0.77 LTB4R (0.56) SRD5A2NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5969146-A MONOAMINE OXIDASE INHIBITORS SYNTHELABO (FR) 1999-10-19 US disclosed
EP-0891358-A1 OXAZOLIDIN-2-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1999-01-20 EP disclosed
WO-1997013768-A1 OXAZOLIDIN-2-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1997-04-17 WO disclosed