Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569154 | 0.96 | TBXAS1 (0.62) | TBXAS1TDP1L3MBTL1CYP2A6PTAFR | |
| SCHEMBL7510148 | 0.94 | TBXAS1 (0.63) | TBXAS1TDP1L3MBTL1CYP2A6PTAFR | |
| SCHEMBL9520246 | 0.82 | TBXAS1 (0.62) | TBXAS1TDP1L3MBTL1CYP2A6HRH1 | |
| SCHEMBL6572384 | 0.82 | LMNA (0.63) | TDP1LMNAPKM | |
| SCHEMBL12197971 | 0.81 | TDP1 (0.62) | TBXAS1TDP1L3MBTL1CYP2A6HRH1 | |
| Bicarbonate SCHEMBL9520631 | 0.81 | TBXAS1 (0.64) | TBXAS1TDP1L3MBTL1CYP2A6PTAFR | |
| SCHEMBL19176893 | 0.81 | TBXAS1 (0.60) | TBXAS1TDP1L3MBTL1CYP2A6PTAFR | |
| SCHEMBL7165228 | 0.80 | TBXAS1 (0.68) | TBXAS1TDP1L3MBTL1CYP2A6HRH1 | |
| Bromide SCHEMBL18838899 | 0.80 | TDP1 (0.61) | TBXAS1TDP1L3MBTL1CYP2A6HRH1 | |
| Acetic Acid SCHEMBL28309069 | 0.79 | TBXAS1 (0.54) | TBXAS1TDP1L3MBTL1LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |