Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | PTAFR | P25105 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510148 | 0.99 | TBXAS1 (0.63) | TBXAS1TDP1L3MBTL1HRH1PTAFR | |
| SCHEMBL7448948 | 0.96 | TBXAS1 (0.56) | TBXAS1TDP1L3MBTL1HRH1PTAFR | |
| Bicarbonate SCHEMBL9520631 | 0.83 | TBXAS1 (0.64) | TBXAS1TDP1L3MBTL1HRH1PTAFR | |
| SCHEMBL6571377 | 0.82 | LMNA (0.57) | MAPT | |
| SCHEMBL6570937 | 0.81 | MAPT (0.59) | MAPTTRPV1 | |
| SCHEMBL7760926 | 0.81 | TDP1 (0.64) | TBXAS1TDP1L3MBTL1HRH1CYP2A6 | |
| SCHEMBL12197971 | 0.80 | TDP1 (0.62) | TBXAS1TDP1L3MBTL1HRH1CYP2A6 | |
| Bromide SCHEMBL18838899 | 0.79 | TDP1 (0.61) | TBXAS1TDP1L3MBTL1HRH1CYP2A6 | |
| SCHEMBL9520246 | 0.78 | TBXAS1 (0.62) | TBXAS1TDP1L3MBTL1HRH1CYP2A6 | |
| Acetic Acid SCHEMBL28309069 | 0.78 | TBXAS1 (0.54) | TBXAS1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |