Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449087 | 1.00 | HRH4 (0.40) | HRH4ACEMMECYP3A4CYP2C19 | |
| SCHEMBL7357061 | 0.83 | ACE (0.49) | ACEMMEALOX15KDM4ETSHR | |
| SCHEMBL3865826 | 0.83 | ACE (0.49) | ACEMMEALOX15KDM4ETSHR | |
| SCHEMBL7443272 | 0.82 | HRH4 (0.42) | HRH4ACEMMEGAA | |
| SCHEMBL7443268 | 0.82 | HRH4 (0.42) | HRH4ACEMMEGAA | |
| SCHEMBL7441321 | 0.79 | THRB (0.40) | CYP3A4CYP2C19ALOX15KDM4ETSHR | |
| SCHEMBL7501387 | 0.71 | ALOX15 (0.43) | MMECYP3A4CYP2C19ALOX15KDM4E | |
| SCHEMBL8212856 | 0.71 | ALOX15 (0.43) | MMECYP3A4CYP2C19ALOX15KDM4E | |
| SCHEMBL7450646 | 0.70 | HRH4 (0.57) | HRH4ACEMME | |
| SCHEMBL7450649 | 0.70 | HRH4 (0.57) | HRH4ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026719-A1 | MERCAPTO-AMIDE DERIVATIVES USEFUL AS NEUTRAL ENDOPEPTIDASE AND ACE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |