Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SDCBP | O00560 | 2/20 | 0.42 |
| ▸ | SDC2 | P34741 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212856 | 1.00 | ALOX15 (0.43) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL7441321 | 0.85 | THRB (0.40) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL7340893 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRXIAPTDP1L3MBTL1 | |
| SCHEMBL7442234 | 0.78 | OPRM1 (0.51) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL7357061 | 0.76 | ACE (0.49) | ALOX15KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL3865826 | 0.76 | ACE (0.49) | ALOX15KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL311675 | 0.76 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2013546 | 0.76 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL30856522 | 0.76 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL7449096 | 0.71 | HRH4 (0.40) | ALOX15KDM4EALDH1A1TSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026719-A1 | MERCAPTO-AMIDE DERIVATIVES USEFUL AS NEUTRAL ENDOPEPTIDASE AND ACE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |