Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 3/20 | 0.56 |
| ▸ | CDC7 | O00311 | 2/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.56 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621308 | 0.79 | MAPK14 (0.62) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL2581961 | 0.77 | VCP (0.59) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL13403220 | 0.77 | CDC7 (0.51) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL13039335 | 0.74 | CDK1 (0.60) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL13039338 | 0.74 | CDK1 (0.60) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL13384574 | 0.73 | IDH1 (0.53) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL2834000 | 0.72 | ASPH (0.55) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL14591578 | 0.72 | VCP (0.51) | VCPGSK3BCDC7MAP4K4ROCK2 | |
| SCHEMBL3779871 | 0.72 | CDK2 (1.00) | GSK3BCDC7MAP4K4ROCK2CCNB2 | |
| SCHEMBL7471338 | 0.72 | MKNK1 (0.51) | ROCK2MKNK2PRKD3PRKCGABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |