Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 12/20 | 0.53 |
| ▸ | CTSL | P07711 | 12/20 | 0.48 |
| ▸ | CTSS | P25774 | 8/20 | 0.48 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924957 | 0.88 | CTSB (0.54) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6183805 | 0.85 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6182791 | 0.85 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6183809 | 0.85 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6182874 | 0.82 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL7132702 | 0.82 | CTSB (0.48) | CTSBCTSLCTSSCTSK | |
| SCHEMBL5924641 | 0.81 | CTSB (0.49) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6183692 | 0.81 | CTSL (0.67) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7450448 | 0.81 | CTSB (0.58) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL7452244 | 0.80 | CTSB (0.61) | CTSBCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |