Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454287 | 0.88 | TMPRSS15 (0.50) | TMPRSS15PRSS1PRSS2PRSS3PDE10A | |
| SCHEMBL13685570 | 0.78 | — | — | |
| SCHEMBL7439168 | 0.77 | POLB (0.48) | KDM4E | |
| SCHEMBL13685325 | 0.73 | — | — | |
| SCHEMBL22974859 | 0.71 | TMPRSS15 (1.00) | TMPRSS15 | |
| SCHEMBL851218 | 0.70 | PRSS1 (1.00) | PRSS1PRSS2PRSS3 | |
| SCHEMBL7450760 | 0.69 | ITGB3 (0.49) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL27582703 | 0.69 | KDM4E (0.59) | KDM4ECYP2C19 | |
| SCHEMBL2488394 | 0.69 | — | — | |
| SCHEMBL2485488 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | claimed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | claimed |