Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 6/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456270 | 0.81 | F2 (0.49) | F2F10ST14PRSS1PRSS2 | |
| SCHEMBL7122825 | 0.76 | ITGB3 (0.75) | ITGB3ITGA2BF2F10ST14 | |
| Hydrochloric Acid SCHEMBL8040370 | 0.75 | ITGB3 (0.73) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL8410645 | 0.72 | ITGB3 (0.69) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL8407198 | 0.72 | ITGB3 (0.69) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL7291480 | 0.70 | ITGB3 (0.66) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL14273084 | 0.69 | POLB (0.53) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7449717 | 0.69 | TMPRSS15 (0.55) | PRSS1PRSS2PRSS3TMPRSS15 | |
| Iodide SCHEMBL7829929 | 0.69 | ITGB3 (0.64) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL7282886 | 0.69 | ITGB3 (0.65) | ITGB3ITGA2BF2ST14PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | disclosed |