Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.74 |
| ▸ | MMP13 | P45452 | 13/20 | 0.74 |
| ▸ | MMP3 | P08254 | 12/20 | 0.74 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555096 | 0.95 | MMP2 (0.66) | MMP2MMP13MMP3BCAT1MMP1 | |
| SCHEMBL7454871 | 0.85 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7454899 | 0.80 | MMP2 (0.88) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7508942 | 0.79 | MMP13 (0.80) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7450983 | 0.76 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7451531 | 0.75 | MMP13 (0.80) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL9410579 | 0.74 | NPC1 (0.74) | BCAT1NPC1RAB9A | |
| SCHEMBL7446562 | 0.74 | MMP13 (0.74) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7899829 | 0.73 | MMP2 (0.74) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7455165 | 0.70 | MMP13 (0.69) | MMP2MMP13MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | claimed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |