Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.66 |
| ▸ | MMP13 | P45452 | 9/20 | 0.66 |
| ▸ | MMP3 | P08254 | 8/20 | 0.66 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449909 | 0.95 | MMP2 (0.74) | MMP2MMP13MMP3BCAT1NPC1 | |
| SCHEMBL7454899 | 0.85 | MMP2 (0.88) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7454871 | 0.80 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7455165 | 0.76 | MMP13 (0.69) | MMP2MMP13MMP3TP53MMP1 | |
| SCHEMBL7451546 | 0.76 | MMP2 (0.85) | MMP2MMP13MMP3NPC1RAB9A | |
| SCHEMBL7446824 | 0.75 | MMP13 (0.70) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7448202 | 0.75 | MMP2 (0.67) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL9410579 | 0.74 | NPC1 (0.74) | BCAT1NPC1RAB9ATP53KDM4E | |
| SCHEMBL7508942 | 0.73 | MMP13 (0.80) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7456050 | 0.72 | MMP2 (0.63) | MMP2MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |